Best Nerve Pain Relief Supplements – Top Nerve Support Pills

Neuropathy is an intense kind of pain. This pain impacts the nerves, and it can cause incredible discomfort, as well as tingling or numbness in the individual’s extremities. Most often, this condition will impact individuals with diabetes, since approximately 65% of these patients have dealt with some kind of nerve damage. In fact, the leading cause of neuropathy in the United States alone is diabetes.

Still, neuropathy can form from many other causes as well, including physical damage to the nerves directly. Other people may suffer from neuropathy as the result of a genetic issue. The use of nerve pain supplements has become rather commonplace to deal with the pain and inflammation associated with this condition. However, there are many different types of formulas on the market today that can help.

In this guide, users will see the formulas that are the most reliable for consumers in 2021.

Top Neuropathy Pain Relief Supplements of 2021

After analyzing and reviewing many different supplements, the formulas ultimately chosen for this guide include:

  • Nerve Control 911
  • Nuturn Maximum Strength Neuropathy Support Formula
  • Nervala
  • Nerve Renew
  • Nerve Rejuv
  • Nervexol
  • Circle Labs CBD
  • Nuturna Clinical Strength Neuropathy 900
  • Neuro Calm Pro
  • Nervogen Pro
  • Bonus Nerve Pain Guide #1: Neuropathy No More
  • Bonus Nerve Pain Guide #2: Neuropathy Revolution

Read on below to learn how each of these supplements can help.

Nerve Control 911


The first formula on this list comes from a company that has been creating supplements for quite some time – PhytAge Labs. This brand is responsible for producing Nerve Control 911, helping users to eliminate nerve pain that is specifically caused by diabetes and other conditions. It uses natural ingredients, which are condensed into two capsules per day to get relief.

Users that take this formula will find that they also improve their overall muscle control, and they can reduce involuntary movements and reflexes. The formula is also used to trigger the communication between the nervous system and the rest of the body, and it can reduce inflammation.

To create these reactions, the creators behind Nerve Control 911 use marshmallow root and passionflower. There is even one ingredient that the creators only describe as a Malaysian “miracle root.” The creators have incredible faith in the ability of this formula to heal the body, and they state that one woman’s nerve damage was so profoundly healed that she avoided the amputation of a limb.

To get one bottle of Nerve Control 911, the total cost is $69.95.

Nuturna Maximum Strength Neuropathy Support Formula


Nuturna’s Maximum Strength Neuropathy Support Formula provides users with another powerful blend of ingredients, which users can purchase from Amazon.com. It is affordable, though it has an incredibly strong dose for individuals with overwhelming pain.

This remedy contains 18 different vitamins, minerals, and herbs that create a powerful effect. Each one is balanced in a specific way, even though many companies do not provide support in the right dosages. Users that purchase this formula will get the benefit of ingredients like alpha lipoic acid, turmeric, benfotiamine, L-arginine, and other herbal extracts.

To get one bottle of this formula by Nuturna, the total cost is currently $43.



Nervala, which is produced by Barton Nutrition, focuses on reducing tingling, numbness, and pain. The purpose of this formula is to relax the nerves more effectively, reducing the overactive stimulation that is leading to nerve pain in the first place. It eases inflammation, reducing the free radicals in the body. These free radicals can cause oxidation and trigger neuropathy.

To relieve the stress and inflammation in the nerves, users only need 75mg of benfotiamine and 600mg of alpha-lipoic acid from this formula. While other products focus on bringing more ingredients to consumers, this combination can be incredibly effective.

To get one bottle of Nervala, the total cost is $67.

Nerve Renew


Nerve Renew is a product of Life Renew, using a blend of alpha-lipoic acid and an assortment of B vitamins to relieve the body of nerve pain. Users only need two capsules a day, and the formula nourishes the damaged nerves with antioxidants to reduce numbness, discomfort, and other issues that plagued this area of the body.

To make this formula effective, the creators behind Nerve Renew state that the ingredients are able to absorb into the body up to three times faster than other formulas as the result of a delivery system. Users don’t need to do anything to make the formula work faster, but it will also provide them with a natural increase in their energy.

To get one bottle of Nerve Renew, the total cost is $59.

Nerve Rejuv


Nerve Rejuv comes from Golden After 50 and is specifically meant for older consumers that are dealing with neuropathy. With two capsules taken daily, users can reduce the typical symptoms of neuropathy (which include pain, numbness, and tingling.

To get these benefits, the formula includes ingredients like alpha lipoic acid, turmeric, and others. The purpose of these ingredients is to help regenerate the damaged nerve endings, which theoretically will eliminate the pain that is often associated with neuropathy. The formula also includes amino acids, herbal extracts, vitamins, and minerals. Rather than simply targeting neuropathy that occurs in diabetes, this formula also deals with the onset of fibromyalgia, shingles, and other conditions that are prone to neuropathy.

The total cost of one bottle of Nerve Rejuv is $59.



Nervexol originally was launched in the supplement industry last year, using ingredients like alpha-lipoic acid, coenzyme Q10, vitamin B1, and Calamarine. B vitamins are rather popular in nerve pain supplements, but this is one of the few formulas that actually includes a deep-sea squid in the ingredients. Calamarine is an incredible source of omega-3 fatty acids, which are needed for the health of the brain, joints, and eyes.

With this blender, users are able to provide new strength and support to the nerves to reduce pain, burning, tingling, and stinging.

To get one bottle of Nervexol, the total cost is $69.

Circle Labs CBD


Circle Labs provides users with many different formulas that are based on the use of CBD. CBD has become rather helpful for individuals that suffer from neuropathy, due to the way that this can nab annoyed can reduce inflammation. The company produces balms, tinctures, and creams for topical support, rather than ingesting another supplement. This formula is completely natural, activating the endocannabinoids system that is directly linked to the central nervous system through CB1 and CB2 receptors.

The brand itself offers many different formulas that users can integrate to treat their neuropathy or any other pain related to inflammation. Circle Labs CBD products typically range from $20 to $75, depending on the type of product chosen and the size of the package.

Nuturna Clinical Strength Neuropathy 900


Clinical Strength Neuropathy 900 is the second supplement on this list that comes directly from Nuturna. The purpose of this formula is to eliminate the pain of neuropathy, and it is sold by many major retailers online. This particular formula can be found on Amazon.com, though users should act quickly because it frequently is sold out.

This formula starts with alpha-lipoic acid, which is paired with organic turmeric root, L-arginine, acetyl-L-carnitine, and other extracts. The formula is a combination of 18 ingredients, and each bottle by Nuturna costs $49.

Neuro Calm Pro


Neuro Calm Pro is one of the few formulas on this list that doesn’t just focus on neuropathy. Instead, it acts as both a supplement for nerve health and for tinnitus. The natural ingredients help to soothe the damaged nerves, which are found throughout the body. In fact, this formula focuses on tinnitus because the constant ringing in an individual’s ears can be the result of nerve damage.

The formula was created by a researcher named Gerard Watson, using natural ingredients like fenugreek extract, saw palmetto, wild yam, and L-tyrosine. The company is also responsible for selling a supplement called Neuro Deep Calm, which claims many of the same benefits. Ordering this bottle of Neuro Calm Pro for $69 will also give users a recording of digital sound therapy to help with the ringing in the ears for free.

Nervogen Pro


Nervogen Pro provides users with five active ingredients that are meant to target the pain associated with the nerves. Those five ingredients include California poppy seed extract, marshmallow root, passionflower, corydalis, and prickly pear extract. Based on the clinical studies cited by the creators, this combo was meant to alleviate the pain, numbness, and tingling of the nerves.

Even though this formula is included on the list, it ranks at the bottom for the low dosages of each of the powerful ingredients. Plus, it is higher priced than some of the formulas that have a higher concentration of those ingredients. For that reason, this guide specifically recommends the formula for mild support, rather than a severe case of neuropathy. Still, users can purchase Nervogen Pro for $69 per bottle.

Bonus #1: Neuropathy No More


While neuropathy supplements can help many people, this guide includes two other options for individuals that want to alleviate neuropathy in a different way. In the guide “Neuropathy No More,” users get information from Blue Heron Health News to show different protocols that they can integrate into their life to erase neuropathy.

The recommendations in this guide include changes to the user’s lifestyle and current diet, helping them get away from medications or strange therapies. The creators of this $49 guide offer a refund policy for the first 60 days in case the plan does not work.

Bonus #2: Neuropathy Revolution


Neuropathy Revolution is the second and final bonus on this list since it is also in the form of a guide. The creators claim that users can eliminate diabetic nerve pain within one month, using holistic methods that do not involve any medication. The process takes 7 steps, and the creators claim that users can stop the pain within a matter of 24 hours.

The guide automatically qualifies users for a free gift, which is another digital guide. The guide is called Diabetes Protocol, helping users to eliminate their struggle with high blood sugar as a way to treat neuropathy. Users can purchase this guide for $37.

How Were the Rankings Chosen?

The only way that this guide was able to come together was with specific standards that each of these formulas had to meet. The bonus guides were simply included because they help to alleviate neuropathic pain, but they were not supplements. Supplements had to meet the following criteria to be considered.

Ingredients that actually work

Considering how widespread neuropathy is for consumers nowadays, the extracts, vitamins, and minerals that were used in these formulas had to have support from the scientific community to show that they were effective.

The right dosage

While the ingredients played a substantial role, the formula would only be effective if the dosage were high enough to make an impact. Formulas with proprietary blends tend to hide the amount of each of the ingredients, making it impossible to predict how effective they could possibly be. This guide prioritized formulas that were clear and transparent about the ingredients used.

Cost and value

To get a reliable neuropathy supplement, consumers will need to spend between $20 and $100. To make sure that users could get a formula that was worth the price, the guide includes a wide range of ingredients at different prices to meet different budgets.

Honesty about the potential benefits

Some creators of supplements go too far when they predict what these formulas can do for the body. Curing a major health condition is highly unlikely but supporting the health of the nerves and helping to manage high blood sugar are more realistic claims. By law, no supplement can claim that it can cure any disease or prevent them, and this guide prioritized companies that are honest about what they could do.

Transparency on the label

The first thing that any customer checks are the label on a supplement. Consumers need to know exactly what they’re putting into their bodies at all times, especially if they are struggling with a condition like diabetes or fibromyalgia. Showing all of these ingredients is important for anyone that needs to make a nutritional choice.

The reputation of the brand

The companies that are known for their reliability and transparency earned a higher place on this list than others. While the length of time a company has served the public did not determine if they were ranked on the list, the reputation they had amongst consumers did.

Presence of a medical advisory board

The top supplement companies on the market today have a staff of medical doctors, naturopathic doctors, and other professionals from the health industry. Companies that made this investment earned a priority over the ones that didn’t.

Benefits that can be proven

Simply put, neuropathy supplements that work are incredibly popular. These products tend to speak for themselves, which is why this guide considered the experiences of customers and the results of lab tests in creating this list.

What Scientific Evidence Supports the Use of Nerve Pain Relief Supplements?

Supplements are not required to engage in certain clinical trials, and the Food and Drug Administration specifically, does not approve or deny the formulas to be sold. Still, there is plenty of research available that shows how the ingredients in these supplements can work. Having the right ingredients can make a big difference in neuropathic pain.


One of the most popular ingredients to include in these types of supplements is acetyl-L-carnitine. The body already naturally produces it in the liver and kidneys, though consumers will also add it to their daily routine to support the energy that their body and mind need. While some studies show that it is commonly associated with relief from neuropathy, other studies have not shown enough of an impact to confirm this use with certainty.

B vitamins

B vitamins are rather common in neuropathy supplements as well, especially vitamins B6 and B12. One study in 2014 discovered that the lack of vitamin B12 in Canada leads to dysfunction of the nerves, as well as other health concerns. If an individual is experiencing neuropathic pain in their feet, vitamin B12 deficiency is rather common. Using this type of vitamin can help tremendously.

That study also examined the effects of vitamin B6 on neuropathy. Interestingly, a deficiency in vitamin B6 can also lead to numbness and/or burning pain in the feet. The sensation often climbs up the legs and eventually affects the hands as well. Using a supplement with vitamin B6 can help with this problem.

Alpha-lipoic acid

Alpha-lipoic acid is found in many of the supplements on this list, providing users with a reaction that is similar to that of antioxidants. It often only takes a few weeks to make a difference, though having a higher dosage in a supplement could result in side effects. Still, introducing alpha-lipoic acid to the body can reduce inflammation and improve blood flow, particularly in the upper arms.


Magnesium has been loosely linked to helping individuals that go through chemotherapy to alleviate neuropathy. However, there is not much research on this particular use. Individuals that have higher amounts of magnesium in their body while they undergo chemotherapy have a reduced risk of neuropathy, but some studies have not backed up this benefit.


Glutamine, which is an amino acid, naturally occurs in the body, reducing the user’s risk of inflammation, muscle pain, numbness, and tingling. Users can take a supplement that only has glutamine, or they can choose the neuropathy supplements that include it in the ingredient profile. Glutamine is found in peanuts, corn, soybeans, milk, wheat, and egg whites. While it is not a cure for neuropathy, using glutamine can reduce the overall severity experienced by patients undergoing chemotherapy.


Glutathione, which is an antioxidant, is found in many supplements that particularly help chemotherapy patients to eliminate neuropathy. It also helps with diabetic neuropathy and neuropathy brought on by other health conditions. However, the digestive process can destroy most of the glutathione before it ever makes it to the bloodstream, which is why supplements often have a difficult time making it bioavailable enough.

Apart from the many ingredients that can be used to help me with neuropathy, lifestyle and dietary changes can also be made to help. Making the effort to reduce blood sugar and getting regular physical activity are just a few changes that users can make. Anyone who smokes cigarettes regularly should consider breaking the habit, and adults who have had chickenpox as children should be vaccinated for shingles. Anything that can be done to improve blood flow or reduce inflammation will also help in the natural effort to ease neuropathic pain.

Most importantly, neuropathy is no laughing matter. Anyone that experiences the symptoms of the condition should speak with a doctor as soon as possible. Severe cases will need more attention than a natural supplement, and this treatment plan should be discussed with a medical professional as soon as possible.

FAQs About Neuropathy Supplements

Q: What is neuropathy?

A: Neuropathy is caused when the nerves are damaged or compressed beyond the spinal cord or brain. It is a chronic condition, and it causes the user to experience pain, numbness, and discomfort.

Q: What is peripheral neuropathy?

A: Peripheral neuropathy and neuropathy are exactly the same. There is no difference between these two conditions.

Q: How does mononeuropathy differ from polyneuropathy?

A: The difference is in the number of nerves that are affected. While mononeuropathy specifically impacts one nerve, polyneuropathy occurs when the condition impacts multiple nerves instead.

Q: What are the symptoms associated with neuropathy?

A: Numbness, pain, tingling, weakness in the hands and feet, and burning are all typical experiences for someone who is dealing with neuropathy. Sometimes, these sensations can be felt up the arms and legs as well. Neuropathy is fairly similar to the sensation that consumers feel when they have an extremity “fall asleep.”

Q: What is the cause of neuropathy?

A: Neuropathy is the result of damage or destruction of nerves. The nerves are used by the brain to send signals. The damage prevents the nerves from correctly communicating with the brain, sending a warped signal that causes an individual to feel the numbness, tingling, and pain of this condition.

Q: How is neuropathy medically treated?

A: The treatment of this condition entirely depends on the patient and the doctor treating them. While some doctors will recommend pain medication or physical therapy, others will use a topical remedy. Laser therapy is also commonly recommended, but the medical industry largely focuses on the symptoms instead of the main cause.

Q: What occurs during neuropathy surgery?

A: This type of surgery decompresses the nerves, and it is typically done as an outpatient procedure (which means that the patient should be able to check out of the hospital on the same day). The surgery is used to alleviate the pressure on compression points on the specific nerve impacted. Some doctors believe that the pressure on these areas is the reason behind the nerve damage.

Q: Why does neuropathy vary from person to person?

A: The condition is complex. Every person experiences neuropathy in a different way, depending on the way that the damage occurred and the nerves that are impacted. While some people experience neuropathy as the result of a loss of communication between the nerve and the brain, others have overactive nerves that send signals when they shouldn’t. The nerves can also signal the brain incorrectly, changing the communication from what it should be.

Q: Is neuropathy painful?

A: It depends on the individual who is experiencing neuropathy. While some of the pain can be rather mild, others experience extreme and severe pain. The severity of the pain is a sign of how serious the damage actually might be.

Q: What nerves can be impacted by neuropathy?

A: The three main types of nerves that can be affected by neuropathy include motor nerves, sensory nerves, and autonomic nerves. Motor nerves control actions like walking and talking, which respond as the result of intentional and conscious movements. Sensory nerves are the nerves that respond to physical touch and send signals associated with temperature and pain. Autonomic nerves are associated with breathing, digestion, and other conscious activities that do not require effort by the individual.

Q: What is the most common reason that consumers experience peripheral neuropathy?

A: Physical injury is one of the most common ways that an individual can damage their nerves. It can occur as the result of something as simple as a fall or as severe as a broken bone. Engaging in repetitive movements frequently can also cause nerve damage, which is how carpal tunnel syndrome occurs. Diabetes, vascular issues, and circulatory damage are all causes as well, preventing the proper functioning of the body.

Lifestyle habits like smoking or taking certain medications can lead to nerve damage. Doctors have also credited problems like kidney disease, liver disease, hormonal changes, infections, and certain types of cancer with being the cause of neuropathy. So much still needs to be researched to fully understand this condition.

Q: How do doctors diagnose neuropathy?

A: Actually, it is rather difficult to diagnose this condition. The symptoms vary from one patient to the next, and the severity is rarely the same – even when the cause is identical. The medical history of the patient is first considered, and they will conduct both a physical and neurological exam on the sufferer. Genetic testing and the testing of bodily fluids occur, and some doctors will order nerve conduction velocity (NCV) tests to learn about the patient’s strength of the nerve signals.

Other possible tests include a nerve biopsy, electromyography (EMG) test, or neurodiagnostic skin biopsy.

Q: Is there any way that consumers can prevent neuropathy?

A: Yes. The majority of these cases occur as the result of diabetes, which can be prevented through proper self-care. Some doctors recommend weight loss, taking the extra pressure off of the nerves.

Q: Is neuropathy genetic?

A: Some types of neuropathies are genetic, like Charcot-Marie-Tooth disease. However, the majority of cases occur as the result of lifestyle factors or physical trauma to the nerve.

Q: Can prediabetes cause neuropathy?

A: There is a chance that someone with prediabetes can have neuropathy. It also puts them at a greater risk of developing diabetes, which inherently increases the risk of neuropathy.

Q: How does a neuropathy supplement help the user?

A: While some neuropathy supplements are used to improve circulation and reduce inflammation, others support the body’s need for amino acids, herbs, plant extracts, and other ingredients that offer relief.

Q: What’s the best neuropathy supplement?

A: All of the choices on this list are helpful options for sufferers of neuropathy.

Top Neuropathy Pain Relief Supplements of 2021 Final Thoughts

Neuropathy can be an overwhelming and painful condition, and it often feels like there’s no relief. The use of a supplement can introduce natural ingredients that are easy for the body to handle without the side effects that pain medication can come with. By choosing a supplement that works for an individual’s particular needs, pain relief could be imminent.

This guide shows users many of the top products on the market today to alleviate the stress and discomfort of neuropathy easily. Try one of the Top Neuropathy Pain Relief Supplements of 2021 today to experience much-desired relief.

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