Top-Rated Best Liver Supplements (2024)

No one can survive without a healthy liver, but most people don’t understand all the damage they may be doing over time. The liver is larger than any other solid organ in the entire body, measuring about the same size as a football. It sits just under the rib cage, and it plays a pivotal role in the overall health of the body. Without proper liver function, health can deteriorate rapidly. For that exact reason, liver supplements have risen in popularity with gusto.

A balanced liver supplement will improve the overall liver health of the user, though some products target other areas of the body’s cleansing and digestive systems. They can reduce inflammation and eliminate toxins at a much faster pace than with diet alone.

Many people take supplements daily to support liver health. A good liver supplement targets multiple areas of the organ. Some supplements support inflammation. Others help cleanse toxins from the body.

In this guide, learn about the top liver supplements available on the market this year.

The Rankings of the Best Liver Detox Supplements

After substantial testing and research, the products chosen for this list include:

  • Oweli Liver Detox
  • Organifi Liver Reset
  • 1MD LiverMD
  • Live Conscious LiverWell
  • Amy Myers MD Liver Support
  • Zenith Labs Zenith Detox
  • Gundry MD Complete Liver Support
  • Advanced Bionutritionals Advanced Liver Support
  • PureHealth Research Liver Health Formula
  • ActivatedYou Morning Complete
  • VitaPost Liver Support Plus
  • PhytAge Labs Urgent Liver 911
  • Bonus Guide: The Non-Alcoholic Fatty Liver Disease Solution

Read on below to learn about the impact of each of these supplements on the liver and the rest of the body.

Oweli Liver Detox


Factors like aging, obesity, alcohol abuse, or simply an unhealthy lifestyle can make the liver highly vulnerable to damage. A liver detox supplement can provide support for a healthy liver in the long run and flush out the toxins that cause the damage. The market is filled with a wide range of liver detox products and it can be quite a task to select one of them.

Oweli Liver Detox can be an instant go-to with its powerhouse natural ingredient mix that provides a natural cleanse. Its herbal blend is enriched with ingredients that contain powerful antioxidants like milk thistle which fights off the free radicals that cause the liver to keep flushing out toxins and protect the liver from damage. Minerals like zinc which maintain optimal liver function are also added to the detox mix along with Artichoke extract, dandelion, beetroot, yarrow. These are other premium ingredients that help to reduce stress and liver inflammation.

Being manufactured in FDA licensed facility and GMP-compliant, Oweli Liver Detox offers complete safety and security control along with a 100-day money-back guarantee. This makes it one of the few products in the market having no additives or GMOs and with good customer service.

All in all, Oweli Liver Detox is one of the safest and most effective liver detox options in the market.

Price: $29.99

Organifi Liver Reset


Organifi’s Liver Reset has the backing of one of the most reputable brands for supplements on the market today. It provides the user with incredible superfoods that can improve the liver’s performance. Some of the ingredients that users find include milk thistle, artichoke leaf extract, dandelion root, and Triphala. Nothing is hidden in a proprietary blend, so users can see exactly what, and how much, they get with each capsule.

1MD LiverMD


1MD LiverMD is fairly easy to get ahold of, especially since it is found on Amazon, Walmart, and the official website (among others). It provides the user with many common ingredients to support liver health, including milk thistle extract, ALA, zinc, vitamin E, and selenium.

The brand has a rather positive reputation for developing many different supplements that help users promote improved health. The LiverMD formula is easily one of the more popular remedies from the brand, which might be due to the potent doses of each ingredient.

Live Conscious LiverWell


LiverWell helps users to improve the health of the liver, but it also triggers a heightened metabolism. The user only needs to take two capsules each day to get the desired results, and they can improve detoxification within the liver. It also supports the production of immunity cells and increases metabolism.

The ingredients of this formula include milk thistle, ALA, and NAC.

Amy Myers MD Liver Support


The Liver Support formula by Amy Meyers uses many ingredients to reduce toxins in the body. In doing so, it improves how the liver functions with ingredients like NAC and alpha-lipoic acid.

Users only need to take a capsule each day to improve the liver’s capability to purge toxins.

Zenith Labs Zenith Detox

Zenith Detox is also backed up by a brand that has a good reputation – Zenith Labs. The remedy is backed up by the doctor that helped in its formulation, pushing for detoxification safely. The purpose is to improve the function of the liver through the purging of free radicals.

Zenith Detox isn’t just for the liver; the manufacturer alleges it also helps users eliminate joint pain and promote better stamina. To achieve these effects, the formula includes Setria glutathione, L-methionine, and Schisandra berry extract.

Gundry MD Complete Liver Support

Gundry MD’s Complete Liver Support offers an affordable product among many expensive options on the market today. The website jests that it has everything that someone could need to improve their liver, helping with multiple aspects of the digestive process.

Advanced Bionutritionals Advanced Liver Support

Advanced Liver Support uses ingredients like milk thistle, selenium, glycyrrhizin, alpha-lipoic acid (ALA), phosphatidylcholine, and other substances to improve the user’s health. Instead of one or two capsules, users will need to take four formula capsules each day to make a difference. However, instead of just improving the health of the liver, it also improves brain health. These ingredients are helpful to individuals that struggle with inflammation, and they can reduce their risk of oxidative stress significantly.

To establish more trust from customers, this remedy uses ingredients sourced from around the world but all blending and manufacturing is done in the United States.

PureHealth Research Liver Health Formula

Liver Health Formula from PureHealth Research stands out because it is one of the few formulas created by a naturopathic doctor. Users that incorporate this remedy may find that they feel much younger and seem to have energy constantly. It doesn’t seem to be exclusively for the liver, but rather the full digestive systems.

The formulation includes ginger, beetroot, and alfalfa. It also includes a few ingredients that have been found on this list of liver support products already, like turmeric, milk thistle, dandelion, and artichoke extract.

ActivatedYou Morning Complete

While every other supplement on this list is included for the specific purpose of detoxifying the liver or improving overall liver function, ActivatedYou Morning Complete is not marketed as either directly. In fact, the purpose of this ingredient is to improve overall health with ingredients like probiotics, green superfoods, fiber, prebiotics, and other nutritious substances that keep the entire body healthy.

This wellness-focused drink is used every single day to prevent oxidative stress from impacting the body. It improves the function of all cells in the body, though it is particularly helpful in managing blood sugar and keeping the liver healthy.

VitaPost Liver Support Plus

VitaPost’s Liver Support Plus is another affordable option, backed by multiple ingredients already seen on this list. Some of those ingredients include zinc, milk thistle, celery seed, artichoke extract, and beet.

Rather than just being available on the official website, users can find the remedy at Walmart and other major retailers as well.

PhytAge Labs Urgent Liver 911

Urgent Liver 911 is automatically backed up with the reputation of its creator – PhytAge Labs. Users will find many already familiar ingredients because of the other remedies on this list. Primarily, they get the benefits of dandelions, artichoke, beetroot, milk thistle extract, and celery seed. However, other ingredients contribute as well. Users might find that they have a similar experience when using Liver Support Plus because the dosage of each ingredient is almost equal.

Some consumers go for this remedy instead due to the longevity and reputation of PhytAge Labs. They have assembled this remedy with 23 different ingredients that can eliminate the buildup of fat from the liver and the toxins that can impede the productivity of the organ.

Bonus Guide: The Non-Alcoholic Fatty Liver Disease Solution

Though all of these products specifically address the problems in the liver with supplements, a guide called The Non-Alcoholic Fatty Liver Disease Solution is also recommended. The guide is included as a bonus because it doesn’t technically fall under the same classification (since it is not a supplement), but that doesn’t mean it has less to offer.

The guide was created by Julissa Clay, who represents Blue Heron Health News. All of the details in this guide deal with making changes for better health. This content is offered as a digital guide, claiming to be the solution for non-alcoholic fatty liver disease. This condition typically occurs when the liver starts collecting too many triglycerides.

How The Rankings Were Determined

Certain requirements had to be met to accurately rank these remedies to ensure that they were truly the top remedies available. The following criteria were considered to make these decisions.

Ingredients that actually work

Every liver health supplement on this list had to have one thing in common – the ingredients had to be proven to work. It isn’t hard to seek out studies to show exactly what each of these remedies can do, and the companies that used this information to create their products were necessary.

The right dosages

Even if the formula has all of the right ingredients, they need to have enough of each to make a difference. Some companies had the right ingredients without the right doses, while others didn’t contain enough of these ingredients even to impact. The supplements that managed to procure a place on the list had to use a clinically proven dose.

Formulated with doctors on staff

The Food and Drug Administration doesn’t regulate supplements, but many doctors lend their expertise to help their development. Some of the top companies on the market today have a staff that includes a medical advisory board, helping to create reliable products.


Companies are only allowed to make certain claims regarding what their products can do. However, bad players will make promises that are impossible to achieve with a simple supplement, like losing 50 lbs. overnight or curing liver disease. The supplements that were more likely to get a spot on this list had to be honest about what they offer.

The reputation of the brand

The companies that have been around for a little time know exactly how to appeal to consumers without overwhelming them. These companies are known for longevity in the industry, providing the necessary transparency to help. Users want to know that companies are being honest with them and the supplements on this list can deliver.

Good prices with the equivalent value

Everyone has a different price that they are willing to pay to improve their health. Some people prefer to cough up $20, while others will go into the triple digits for their health. All of these products have the equivalent value for the price that consumers have to pay.

With these criteria, the rankings were born.

Liver Detox Ingredients: What Does the Science Say?

Finding studies that show exactly what vitamins, minerals, and botanicals can do for the body is rather easy. Some of the remedies found online have already been used for thousands of years, backing up why they are still used today.

Milk thistle is a perfect example. As one of the top ingredients on the market for liver health, milk thistle provides users with a substance called silymarin. This compound has been found to help with the regeneration of liver tissue, which is a breakthrough for any supplement. Furthermore, it can help with inflammation, and it defends the liver cells from the damage they can sustain over time.

As helpful as milk thistle can be, the studies on humans do not show as substantial of a difference. Researchers that examined the reaction of humans to milk thistle found almost no difference in one study. However, reviews have been mixed. Other studies show that milk thistle extract could give children less liver damage when they are undergoing chemotherapy. Another study showed that the presence of silymarin helped to improve the enzymes in the liver and reduced the risk of diseases like hepatitis B, hepatitis C, and cirrhosis.

Artichoke is another ingredient that keeps being included in these types of remedies. The purpose of the artichoke leaf is to eliminate the toxins in the body, though one study reveals that it can even help with the regeneration of liver cells. Individuals with non-alcoholic fatty liver disease were able to reduce the damage that they’d sustained by including artichoke leaves in their diet.

Dandelion root has minimal information on the full effects that it can have. It is so new in the industry that hardly any clinical studies are performed at a large-scale capacity to help users understand how it works for the liver consistently. In one study, researchers examined the reaction that it had as an anti-inflammatory, anti-oxidative, and anti-carcinogenic supplement with positive reception.

Zinc is more familiar in the industry, though most people know it as an immunity booster. Individuals that struggle with chronic liver disease are typically unable to maintain enough zinc in the body to prevent deficiency. Using zinc every day can reduce the risk of oxidative damage.

Some formulas swear by the use of licorice root as their main ingredient. A trial in 2012 revealed that the use of licorice root for people with chronic hepatitis C had a major change in their symptoms for the better. It also helped to reduce inflammation and weight gain in rats during a separate study. As helpful as this ingredient could be, consuming too much licorice extract can be dangerous for the body.

Turmeric has earned a special place in the world of liver-boosting supplements because it reduces inflammation and keeps pain in the joints down. However, it is specifically beneficial to the liver because it can improve liver health and reduce the impact of hepatic disorders.

While yellow dock root isn’t quite as well known, the science behind its use seems to back it up as a remedy for the liver’s health. It typically is sourced from a type of tea, and it can reduce the toxins in the body with ease. It has a diuretic impact, and it can help users eliminate the excess waste that might be built up in the liver. It improves the release of water and mucus for the colon, improving the way the liver functions.

This is far from a complete list of all the formulas and ingredients that can help users improve their liver health. Ingredients like beetroot, ginger, choline, molybdenum, selenium, and alpha-lipoic acid offer help to users nowadays. Finding supplements that use these ingredients is likely to have a lasting impact that can easily help the liver.

Signs That Your Liver Needs Help

Far too many people put off their liver health because they simply don’t know they are in danger. Considering the amount of space that the liver takes up, more people need to know what to look out for when they are not feeling their best. After all, keeping the liver healthy is the key to keeping many other organs healthy as well.

Here are a few signs that the liver may not be working like it is supposed to:

  • Frequent fatigue and physical weakness.
  • Reduced appetite.
  • Accidental weight loss.
  • Nausea, which is sometimes accompanied by vomiting.
  • Urinating with a dark yellow hue.
  • Passing gray stools.
  • Discomfort or reduced movement around the bottom of the ribcage.

Liver issues should not be ignored, as they often lead to substantially worse and more serious problems. Bleeding and bruising easily are other signs of these problems, as are fluid retention and confusion. Some people even go through memory loss because they wait too long to see a medical professional. Realistically, the treatment that goes into liver damage isn’t complicated, and it can easily be dealt with early on. Always consult with a doctor to ensure that the liver remains strong and healthy.

Natural Ways to Promote A Healthier Liver

All of the supplements listed in this guide are helpful ways to keep the liver healthy. However, some people want to make more of an effort in their own life, which is why changes to the diet and their current lifestyle can help.

Some of the recommended ways to improve the liver include:

  • Reducing the amount of fat in the diet, especially saturated fat can create deposits around the liver.
  • Use a daily liver health supplement, which can help with inflammation and detoxification.
  • Reduce the amount of alcohol consumed regularly, which can cause the release of toxic chemicals in the liver.
  • Reduce how many cigarettes the individual consumes daily, reducing the risk of inflammation from the toxic substances used to create them.
  • Ease the amount of exposure to different toxins that can influence the liver’s health, which can be found in cleaning products and air quality.
  • Abstaining from illegal drug use, which can irritate the liver.
  • Manage the use of medications safely.

By making these changes, anyone can be on their way to improved health within the liver and the rest of the body.

Frequently Asked Questions About Liver Health Supplements

Q: What exactly is a liver supplement?

A: A liver supplement provides the user with natural ingredients that can support the health of this important organ.

Q: What is the liver?

A: The liver is an organ found in all humans, eliminating the toxins that build up due to diet and environmental factors. It sits just below the rib cage, and it is about the same size as a football.

Q: How can a liver supplement help the user?

A: The majority of the liver supplements on the market today specifically focus on detoxification, impacting the kidneys and the liver alike. They also protect the cells in the liver from becoming inflamed, and they improve the overall function of this large organ. The liver also has a substantial impact on the immune system’s effectiveness, which is why these supplements often support the need for immunity boosting as well.

Q: How are users supposed to take liver supplements?

A: The majority of these supplements are available as a capsule. The directions will vary from one product to the next. Supplements that come in a powder form will need to be scooped into a liquid to prepare the drink.

Q: Which liver supplement is the best one?

A: There are many options available to consumers nowadays. This list is a guide to the top remedies on the market today.

Q: What is the role of the liver?

A: The purpose of the liver is primarily 2 handle the nutrients that the intestines have already absorbed. It also regulates the blood as the nutrients from protein, fats, and sugar are added. The liver eradicates old red blood cells, and there are several chemicals that the liver creates to help with blood clotting. The liver is essential for the metabolizing of medication and alcohol. However, there are many other functions to consider.

Q: What is the cause of liver damage?

A: Damage to the liver can happen for many reasons. Primarily, lifestyle factors and the diets that the individual consumes place the biggest role. The liver can also become damaged from using too many medications and other drugs and heavy alcohol consumption. Hepatitis is one of the known medical conditions that can cause liver damage as well.

Q: Can liver disease be genetically inherited?

A: Some types of liver disease are genetic, but most of these problems come from lifestyle factors.

Q: What are the signs of a liver problem?

A: The most common indications that an individual is dealing with liver disease include bloating, fatigue, constipation, gas, jaundice or yellowing in the eyes, struggling to lose weight, and high blood pressure. Other signs may include dark urine, depression, fluctuating moods, perspiration, and an imbalanced appetite. Most often, individuals with liver problems will also develop bruises much easier.

Q: What can consumers do to cleanse their liver?

A: Maintaining a healthy diet for a few weeks can have an incredible effect on the liver’s health. Some users pursue juice cleanses to help as well.

Q: Is liver damage reversible?

A: Yes. This organ has the unique ability to regenerate, rather than scarring as other organs do. Treating the liver currently can reverse most types of liver damage.

Q: Should every person take a liver supplement?

A: Every person is different, and many people have a perfectly healthy liver that will never need such a supplement. Unsure individuals should speak with their doctor first.

Q: What is the most likely cause of liver disease for individuals that live within the United States?

A: Alcohol abuse is the most common reason that Americans suffer from liver disease.

Q: Is the liver the largest organ?

A: Technically, no. The skin is the largest organ. As far as the organs within the body, the liver is the largest.

Q: Is hepatitis a type of liver disease?

A: Yes. The word literally translates to mean “inflammation of the liver,” which is a disease symptom.

Q: What is cirrhosis?

A: Cirrhosis is the medical term for chronic liver disease in its late stages. The liver is meant to help prepare itself, but the scarring that occurs with cirrhosis prevents it from using those regenerative cells.

Q: What does a doctor do to determine the health of the liver?

A: The professional will make the user go through a hepatic function panel, which includes multiple blood tests that test inflammation, infections, and other issues related to liver disease.

Q: Is it important to regularly participate in liver detoxification?

A: Scientific evidence still does not show that detox can positively help the liver. The purpose of the liver is to eliminate toxins naturally, and the only way it will not do so is if the liver is unhealthy. Maintaining a healthy diet will offer many more benefits than detoxes or cleanses.

Q: What’s the best diet for liver health?

A: Currently, there is no specific diet that benefits the liver more than any other eating plan. Maintaining a healthy diet is the goal, though some people particularly enjoy the Mediterranean diet rich with high fiber foods and whole-grain bread. Users that want to reduce their risk of liver disease should avoid saturated fats, salt, sugar, alcohol, and fried foods.

Q: Do liver supplements work?

A: Yes, but it depends on the problem. The majority of the ingredients found in these formulas can support liver health, while others focus on inflammation and function. Users that suspect that something is wrong with their liver should probably speak with a medical professional for further evaluation as well.

Q: Are liver supplements safe?

A: Yes. Using a liver supplement with the recommended directions can be incredibly helpful. However, individuals who currently have a medication prescribed should speak with a medical professional before integrating any new formula.

Q: Could a supplement be damaging to the liver?

A: No. As long as the user follows the instructions laid out for them, no damage will be done. Interestingly, studies show that about one-fifth of the liver injuries that Americans sustain result from using herbal dietary supplements outside of liver health supplements.

Q: What is fatty liver?

A: This condition means that the cells of the liver have fat deposits on them. The issue can be reversed, though it is originally caused by diet choices, lifestyle factors, and genetics. If left untreated, it can lead to cirrhosis of the liver.

Q: What is NAFLD?

A: NAFLD is a non-alcoholic fatty liver disease, and it covers a broad range of liver issues. All of these issues go back to the buildup of fat in the liver.

Comparing Liver Products At a Glance

Oweli Liver Detox
  • Complete Liver Health Formula
  • Money Back Guarantee
  • Organifi Liver Reset
  • Popular User Brand
  • Good Value
  • 1MD LiverMD
  • Doctor-Formulated
  • Convenient Dosing
  • Live Conscious LiverWell
  • Organic Formulation
  • Low Retail Price
  • Amy Myers MD Liver Support
  • High Potency Formula
  • Doctor Developed
  • The Best Liver Detox Supplements of 2024 Final Thoughts

    The use of liver detox supplements can be beneficial to the user’s health. The liver controls the filtration of the entire body, which makes it incomparably important to the other systems in the body. Using ingredients like milk thistle, artichoke, and zinc are just a few ways that the body can nourish this necessary organ to improve the rest of the user’s health. By using the right ingredients, anyone can reduce the inflammation that can further irritate the body.


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