Best Nootropics That Work: Ranking the Top Brand Picks to Buy

Nootropics supplements earned their popularity for consistent and incredible benefits for the health of the brain. They support memory and cognition, though they also provide support to be more focused every day.

Every nootropic works in the same way – triggering improved blood flow. However, the ingredients that trigger these responses are quite different. Some remedies include plants and herbal extracts, while others use vitamins and minerals.

Anyone stands to benefit significantly from the use of nootropic supplements, even if they are an older adult or a college student. Blue-collar workers and prominent CEOs equally benefit. However, new supplements fill the market every day, and choosing the right formula becomes even more critical when it is a matter of brain health.

This guide helps anyone decide on the best nootropic supplement for them, especially in the thriving economy of 2021.

The 33 Best Nootropic Supplements in 2021

Since every supplement tends to say the same claims, this guide allows users to understand the top products on the market. With hundreds of options, these 33 nootropic products offer the best results.

SANE Vitaae: The “Brain Trick” boosts brain energy by 90%
Mind Lab Pro: Independent research has proven Mind Lab Pro’s effectiveness in boosting cognitive function and memory retention power
Nuzena Neuro Focus +: Optimizing brain function with this formula is super simple
NooBru: One of the best cognitive enhancers to maximize brain potential and mental function
Nootrogen: 100% natural nootropic formula that can improve mental performance and cognitive function
Ageless Brain: 11 high-quality ingredients for supporting cognitive function and brain cells
Onnit Alpha Brain: Carefully selected ingredients in Alpha Brain provide daily cognitive support
Hunter Focus: You can get faster results for focus with this premium nootropic supplement
Qualia Mind: This nootropic supplement is an advanced blend of natural components for boosting brain function
Performance Lab Mind: Performance Lab Mind is termed as an ultramodern nootropic supplement
Vital Plan Brain Boost: Physicians have developed it to target poor mental health and brain function
NaturalCell NeuroActiv6: A formula that can improve cognitive function and give faster results
Synapse XT: Healthier brain and hearing with a natural approach called Synapse XT
NooCube: It contains ingredients that promote a healthy brain function thoroughly
Natural Stacks NeuroFuel: This original CILTEP® blend starts working within just 30 minutes
UpWellness Mind & Mood: It is among the top nootropic supplements for stress and anxiety
PureEssence BrainEssence: It presents the world’s most powerful nootropic nutrients
PureHealth Research Ageless Brain: A unique and premium nootropic supplement
Brain C-13: Made by doctors, this nootropic supplement promotes brain function with the help of herbs
Cymbiotika Golden Mind: A formulation of all advanced brain nutrients
Elm & Rye Nootropics: This preoperatory blend can boost cognitive function and concentration
CogniBiotics: A new probiotic formula for better gut and brain health
Amy Myers MD NeuroLive: A medically formulated solution containing seven micronutrients that support the brain cells and functions
Neuro: Your brain will benefit greatly from these functional gums
OptiMind: It enhances concentration and energy by using premium ingredients
Youthful Brain: Formulated by Doctor Sam Walters, an expert
Oweli Neuro: This formula is capable of boosting your brain potency by 100 times
ReMind Solution: A cognitive enhancer that supports six different performance indicators
Brain Pill: Brain Pill is called a secrete remedy for poor brain function
ProMind Complex: This promotes six unique memory-enhancing techniques through its formula
Memory Hack: This natural brain booster offers quick results
MemoSurge: It is one of the most powerful supplements for improving brain function
Memo Defend: 100% effective and pure ‘Work Of Art’ for healthy brain function

Learn a little bit more information about each one by reading below.

SANE Vitaae

Supplement Description
What’s In There? Vitamin D, folate, acetyl L-carnitine, omega-3 fatty acids, citicoline, and CoQ10
Quantity In Each Pack: 45 pills
Right Serving: The daily dose is three capsules
Any Guarantee: 365-day money-back guarantee
SANE Vitaae Price: $47

Vitaae comes from SANE Laboratories, and it is the top formula on this list. Using the power of CoQ10, consumers directly target the inflammation that harms the brain in the first place. It isn’t filled with vitamins and minerals, but the lab tests reveal that consumers generally experience a 13.6% boost in their brain energy and a 26% boost in membrane turnover. However, the benefits keep going.

With daily use, the creators promise improved mental clarity, concentration, and mood. The formula offers incredible pricing, though the value exceeds what users expect.

Mind Lab Pro

Supplement Description
What’s In There? Citicoline, Phosphatidylserine, Bacopa Monnieri, lion’s mane mushroom, and Rhodiola Rosea
Quantity In Each Pack: 60 capsules
Right Serving: Consume Two capsules every day
Any Guarantee: 100% satisfaction guarantee
Mind Lab Pro Price: $69

Mind Lab Pro is incredibly popular, even though it comes with a higher cost. It is the ideal formula for someone who has never tried this type of nootropic supplement. The serving only takes two capsules to get the benefits of 11 ingredients known for their brain-boosting power. The Mind Lab Pro nootropic stack can target brain pathways and promote healthy brain cells for better cognitive functions.

Ensuring that customers get everything they need from this remedy, the creators put each supplement through third-party testing and steer clear of “filler” ingredients. Dr. Ramon Velazquez, a neuroscientist, leads the medical advisory board that developed this formula and all others from the brand.

Nuzena Neuro Focus +

Supplement Description
What’s In There? Users get nutrients like green tea extract, bilberry fruit extract, glutamic acid, DMAE, and other essential ingredients within this blend
Quantity In Each Pack: 60 pills
Right Serving: Take two pills regularly to improve brain function
Any Guarantee: No
Nuzena Neuro Focus + Price: $30

Nuzena’s Neuro Focus + helps users maintain and improve brain function, supporting the brain’s ability to focus on big and small tasks. Developed within the United States exclusively, new customers get a low price on their purchase to ensure that they get as many bottles as possible at a discounted price.

Instead of showing the exact measurements of each vitamin and mineral, a proprietary blend holds it all. However, concealing the combination allows the company to prevent other brands from copying their success.


Supplement Description
What’s In There? Athletes, students, and workers all benefit, thanks to the combination of alpha GPC, L-theanine, Ashwagandha, Huperzine A, and other ingredients with multiple clinical studies behind them
Quantity In Each Pack: Contains 20 servings
Right Serving: Take a serving and mix the powder with any beverage for better cognitive functions
Any Guarantee: A complete risk-free guarantee
NooBru Price: $55

NooBru entices consumers with a tasty and unique flavor, gaining many sales since its launch in 2020.

NooBru’s team focuses on total transparency. There are no proprietary blends to conceal the amount of each ingredient, and users see a clear list of every element used. The ingredients are incredibly potent, which explains why so many people like it.

Users have their choice of Shield or Advantage, though both come as a powder. Mix the powder with any beverage, taking one serving a day to improve immune, cognition, focus, and many other aspects of the user’s health.


Supplement Description
What’s In There? Glutamic acid, L-tyrosine, and DMAE. Plus, there’s a proprietary formula that uses herbal extracts, amino acids, and plant extracts
Quantity In Each Pack: 60 pills
Right Serving: Two-capsule serving
Any Guarantee: No
Nootrogen Price: $30

Nootrogen requires users to take two capsules every day to get the desired mental function, including more energy, better focus, and general support for the brain’s health. At first glance, Nootrogen looks like many of the products are making the same promises. However, the list of ingredients makes it clear that this remedy is here to stand out.

Ageless Brain

Supplement Description
What’s In There? Cat’s claw, guayusa, Camu Camu, cacao, dragon’s blood, and cinnamon
Quantity In Each Pack: Contains 60 capsules
Right Serving: Two pills every single day
Any Guarantee: 365-day money-back guarantee
Ageless Brain Price: $55

Ageless Brain is a product out of Organixx, offering a few familiar ingredients from the rest of this list (like Bacopa Monnieri). Individuals who take this formula often want a change in their routine, but they don’t want the same nootropic formulas they’ve had in the past.

Onnit Alpha Brain

Supplement Description
What’s In There? With each serving, users get Bacopa Monnieri, Cat’s claw, oat straw, and Huperzine A, though it includes other ingredients as well
Quantity In Each Pack: 90 easy to swallow capsules
Right Serving: Serve three capsules every day
Any Guarantee: Risk-free trial
Onnit Alpha Brain Price: $35

Onnit Alpha Brain supports co-owner Joe Rogan, helping users improve their memory, focus, and overall cognition. It supports multiple clinical trials, even though most supplement companies won’t invest in keeping their prices low. By performing clinical studies, users have more confidence in the product they use.

Hunter Focus

Supplement Description
What’s In There? Passionflower, Bacopa Monnieri, and Phosphatidylserine
Quantity In Each Pack: 120 pills
Right Serving: Take four pills every day
Any Guarantee: No
Hunter Focus Price: $60

Hunter Focus from Roar Ambition promises users that it provides a boost during competition. Users get all-natural ingredients, which users have already seen in the ingredient profiles of other products on this list. Made to fight mental fatigue, users get incredibly high doses. Furthermore, the formula boosts mental and physical performance, cognitive function, memory retention power, and mental processing speed.

Qualia Mind

Supplement Description
What’s In There? The nootropic stack has DL-Phenylalanine, Taurine, Citicoline, Artichoke leaf extract, Acetyl-L-Carnitine, Mucuna pruriens, and Phosphatidylserine
Quantity In Each Pack: 154 pills
Right Serving: Serve two pills daily
Any Guarantee: 100-day money-back guarantee
Qualia Mind Price: $59

Qualia Mind from Neurohacker Collective Contains 28 different ingredients that support the user’s need for better focus, memory retention, energy, and overall brain health. This formula is just one of several nootropic supplements that the brand provides. Others include Qualia Mind Caffeine Free, Qualia Mind Essentials, and Qualia Focus.

In addition to the many ingredients, if the user finds this nootropic stack formula is not helpful, they can return it for a refund.

Performance Lab Mind

Supplement Description
What’s In There? Performance Lab Mind Contains Citicoline, Phosphatidylserine, L-tyrosine, and maritime pine bark extract to improve brain function
Quantity In Each Pack: 30 NutriCaps
Right Serving: 1 NutriCap
Any Guarantee: 30-day performance promise
Mind Price: $69

Performance Lab Mind is highly effective and requires daily use to make a difference. Brain energy is easy to boost by at least 13%, and it can promote better motivation and recovery after intense activities that involve the brain. It has Maritime Pine Bark Extract to help brain cell regeneration. Also, it supports brain chemicals to reduce stress. Users get several familiar ingredients in this formula, with antioxidants, vitamins, minerals, and other essential nutrients.

Brain Boost

Supplement Description
What’s In There? The formula includes ingredients like Ginkgo Biloba leaf extract, Bacopa Monnieri, Ashwagandha, Cat’s claw extract, and lion’s mane mushroom to create such a powerful effect
Quantity In Each Pack: 120 pills
Right Serving: Four capsules daily
Any Guarantee: 90-day money-back guarantee
Brain Boost Price: $48

Brain Boost from Vital Plan is one of the few formulas on this list with a doctor on staff. Created by Dr. Bill Rawls, MD, users typically include this supplement in their routine to improve memory, support cognitive function, promote immunity, enhance focus, increase natural energy, and improve the mood. Furthermore, it has a lion’s mane mushroom to support the nerve growth factor. However, the formula doesn’t simply stop at the brain. There are other benefits as well, as support for the microbiome. The labeling is entirely transparent, and users don’t have to worry about proprietary blends.


Supplement Description
What’s In There? The nootropic stack has Ashwagandha, grape seed extract, turmeric, B vitamins, citicoline, and coffee fruit extract
Quantity In Each Pack: Contains 30-day serving
Right Serving: Serve one scoop with your favorite beverage
Any Guarantee: 60-day money-back guarantee
NeuroActiv6 Price: $46 per month

NeuroActiv6 by NaturalCell has plenty of support for users, improving their brain health as focus and clarity get enhanced. Available as a powder, users mix one scoop of the product with any beverage that they choose to get all of the promoted benefits. Some users even find that the remedy improves cortisol levels.

Many of the clinically proven ingredients found in this nootropic stack formula are superfoods, meaning that they have incredible nutritional support for users.

Synapse XT

Supplement Description
What’s In There? Garlic and specific B-Vitamins, Hibiscus, Hawthorn Berry, and Rosemary
Quantity In Each Pack: 60 capsules
Right Serving: Two capsules
Any Guarantee: No
Synapse XT Price: $69

Synapse XT introduces the body to herbs, vitamins, minerals, and implants that may not typically benefit from other nootropic stacks. The formula is more than a nootropic, claiming that it can help with cognitive and hearing concerns. The whole serving is only two capsules daily, which is enough to reduce mental fatigue.

NooCube Brain Productivity

Supplement Description
What’s In There? Alpha GPC, Huperzine A, Cat’s claw extract, and Bacopa Monnieri
Quantity In Each Pack: 60 capsules
Right Serving: Take two pills daily
Any Guarantee: 60-day money-back guarantee
NooCube Brain Productivity Price: $60

NooCube Brain Productivity has the support of the top neuroscientists, though the company does not list all of them by name. There are no forms of caffeine found in this formula, but users get plant extracts, herbal extracts, and other essential ingredients.

Like several other nootropic stacks and smart drugs on this list, the purchase is protected by a money-back guarantee.


Supplement Description
What’s In There? The ingredients used in this formula include artichoke extract, forskolin, acetyl L-carnitine, and vitamin B6, which all promote a stronger brain function
Quantity In Each Pack: Contains 45 pills
Right Serving: Take three pills every day
Any Guarantee: 30 days money-back guarantee
NeuroFuel Price: $30

NeuroFuel from Natural Stacks is relatively similar to the other nootropics and smart drugs, but all the ingredients have one common feature – their sources are on the blockchain. Blockchain technology has been around for quite a while but featuring each element lets users fully understand where they came from. The formula is effective to deal with mental fatigue, brain fog, and poor cognitive function.

Instead of having a small amount of many different ingredients, the creators chose to use potent doses in just a few ingredients. This makes it different than other nootropic stacks.

Mind & Mood

Supplement Description
What’s In There? Includes Rhodiola Rosea, 5-HTP, GABA, saffron, and L-theanine (though it is not a complete list)
Quantity In Each Pack: 90 capsules
Right Serving: Serve three pills daily
Any Guarantee: 60 days money-back guarantee
Mind & Mood Price: $57

Mind & Mood from UpWellness takes a different turn than other formulas do. Most other nootropic supplements and smart drugs enhance the way the brain works to improve cognition in focus. However, this remedy balances the mood to reduce stress and anxiety by restoring brain chemicals.

The creators claim that daily use encourages a more relaxed nervous system, promoting better emotional health. Luckily, the formula’s creation results from work by Dr. Joshua Levitt and Dr. Amanda Levitt.


Supplement Description
What’s In There? Acetyl l-carnitine, Ashwagandha, Bacopa Monnieri extract, Rhodiola Rosea extract, Chinese clubmoss extract, alpha-lipoic acid (Amino Acid), and other ingredients
Quantity In Each Pack: Contains 30 tablets
Right Serving: The user needs two tablets to stimulate the cognitive benefits
Any Guarantee: 90 days money-back guarantee
BrainEssence Price: $30

BrainEssence from PureEssence provides users with a tablet that improves focus, memory, energy, and a better mood. Tablets are used instead of capsules as a supplement. It’s easy to understand BrainEssence’s ingredients and dosages since all ingredients are disclosed upfront.

PureHealth Research Ageless Brain

Supplement Description
What’s In There? Made by Dr. Holly Lucille, users get many B vitamins, caffeine, Huperzine A, and GABA
Quantity In Each Pack: 30 pills
Right Serving: Serve one pill daily
Any Guarantee: 365 days money-back guarantee
Ageless Brain Price: $44

Ageless Brain by PureHealth Research comes with ingredients all contributing to the improved cognition that users experience.

Users only need one capsule a day to get the benefits, but users consume a proprietary blend that doesn’t have the exact amounts of each ingredient in the process.

Brain C-13

Supplement Description
What’s In There? It includes ingredients like rosemary leaf, turmeric, Ginkgo Biloba leaf, Huperzine A, and Phosphatidylserine to offer various cognitive benefits
Quantity In Each Pack: 90 capsules
Right Serving: Take three capsules daily to optimize brain health
Any Guarantee: 180-day money-back guarantee
Brain C-13 Price: $49

Brain C-13 comes from Zenith Labs, and it provides the body with vitamins, minerals, herbs, and plant extracts, providing much of the same mental benefits that other brain supplements offer. Users need to take three capsules a day to get the desired results, but the label features every ingredient upfront. There are no proprietary blends hidden in this product. A medical advisory board and several doctors collaborated to get this formula to customers to improve the quality.

Cymbiotika Golden Mind

Supplement Description
What’s In There? The natural nootropic ingredients in this product include organic phosphatidylcholine, lion’s mane mushroom extract, Rhodiola Rosea, and L-theanine for healthy brain cell growth
Quantity In Each Pack: 30-day serving
Right Serving: Serve 14 pumps every day
Any Guarantee: No
Golden Mind Price: $50

Golden Mind from Cymbiotika stands out as the only liquid tincture available, rather than having a mixable powder or a capsule. However, users still get plenty of nutrients. There are a few others like sea buckthorn oil and Gotu kola extract. This formula makes quite an impression on users, providing 82 ocean minerals as well. The formula supports mental performance, avoids cognitive decline, and enhances cognitive abilities. Also, the Rhodiola Rosea aids in mental processing.

The nootropics stack requires daily use to make the difference, but it can reduce mental fog and keep the brain healthy.

Elm & Rye Nootropics

Supplement Description
What’s In There? The nootropics stack has GABA, Bacopa Monnieri extract, alpha GPC, L-theanine, and L-tyrosine
Quantity In Each Pack: Contains 60 pills
Right Serving: Take two pills to improve mental performance
Any Guarantee: 30-day risk free trial
Elm & Rye Nootropics Price: $85

Elm & Rye Nootropics is one of the most expensive formulas on this list. With natural ingredients, users simulate better productivity and stamina as they improve their attention span. This formula supports mental processing speed and mental acuity.

Part of the reason that this formula provides so much support for energy levels is due to the massive dose of caffeine. It has approximately the same amount of caffeine that two to three cups of coffee have, quickly energizing the user.


Supplement Description
What’s In There? Chaihu-Shugan-San formula and Shen Bu Xin San formula
Quantity In Each Pack: 60 easy to swallow capsules
Right Serving: Two pills
Any Guarantee: 365 days money-back guarantee
CogniBiotics Price: $62

CogniBiotics is all about multitasking. With support for the brain, users experience better mental clarity, improved brain power, and easier learning. Rather than focusing on the brain, the formula also enhances the digestive process to support gut bacteria.

Without the proper support for the guts, cognition becomes compromised. With 17 different adaptogenic and nootropic herbs, users increase their cognitive function with the improved flora of the gut. It even improves the mood. Ten of the ingredients are probiotic strains for the gut, while the rest contribute to the brain.

Amy Myers MD NeuroLive

Supplement Description
What’s In There? It contains ingredients like Mucuna Pruriens, Ginkgo Biloba, and Bacopa Monnieri go into a proprietary blend with other ingredients to fight free radicals
Quantity In Each Pack: 60 capsules
Right Serving: Take two capsules a day to boost cognitive function
Any Guarantee: 90-day money-back guarantee
NeuroLive Price: $49.97

NeuroLive by Amy Myers MD offers powerful nootropic effects that users get from the work of a doctor. Users expect to get the most out of this formula with seven micronutrients, but it isn’t the potent remedy that users receive from other remedies on the list.

Without the same oxidative damage, consumers nourish the brain with performance-enhancing ingredients that support the memory and mental energy that all users need each day. The formula has health benefits that exceed the brain’s health, improving blood flow and maintaining a high-functioning cardiovascular system.


Supplement Description
What’s In There? L-theanine, Natural caffeine, and B-vitamins
Quantity In Each Pack: Contains nine pieces
Right Serving: Take one gum at once
Any Guarantee: Complete happiness guarantee
Neuro Price: $21

Neuro isn’t a pill or a powder, offering nootropic benefits to users as either gum or mint instead. It creates new energy for the user, though it also calms the mind and focuses it. There are three variations – Energy & Focus, Calm & Clarity, and Ideal State. Use it at any time throughout the day, getting a delicious flavor whenever the user pops one in their mouth. Right now, the brand offers cinnamon and peppermint flavors, appealing to consumers with their tasty options.


Supplement Description
What’s In There? The formula’s main ingredient is Bacopa Monnieri with 55% bacosides, which are the active chemicals in the plant
Quantity In Each Pack: Contains 32 capsules
Right Serving: Users only need one serving each day to get the desired effects
Any Guarantee: No
OptiMind Price: $30

OptiMind is a nootropic supplement that improves concentration, focus, and memory by containing 14 nootropic ingredients. A dietary supplement specifically designed to promote cognitive health and developed by Alternascript. OptiMind is all about mental energy, combining the need to improve cognition with improved focus, clarity, and memory retention. Also, this can slow cognitive decline than usual.

Youthful Brain

Supplement Description
What’s In There? Some of the notable elements include vitamin B12, Bacopa Monnieri, and Huperzine A for long term brain health and brain functions
Quantity In Each Pack: 60 pills
Right Serving: Take two capsules daily
Any Guarantee: 180 days money-back guarantee
Youthful Brain Price: $65

Youthful Brain, a remedy by Vitality Now, improves the user’s mental energy as cognition and brain health gain support. It is rich with active ingredients that have a striking similarity to the other products on the list. These ingredients can enhance cognitive function, avoid brain fog and cognitive decline, and promote the production of brain cells.

As good as Youthful Brain is, the low dosages of the ingredients keep it lower on this list of the best nootropic supplements.

Oweli Neuro

Supplement Description
What’s In There? Ingredients like Huperzine A, Bacopa Monnieri, Phosphatidylserine, B vitamins, inositol, and DMAE can help to boost mental performance, brain function, brain energy, and blood flow
Quantity In Each Pack: Contains 60 veggie capsules
Right Serving: Serve two capsules every day
Any Guarantee: 100 days money-back guarantee
Oweli Neuro Price: $30

Oweli Neuro Brain & Focus Formula, which most consumers simply call “Neuro,” creates a Zen-like transformation for users with just two capsules every day. It helps students who need to learn and study, though it is also a powerful remedy for individuals who deal with age-related cognition issues. Most users find that regular use helps with their mood, stress level, and overall productivity.

ReMind Solution

Supplement Description
What’s In There? Bacopa Monnieri, L-glutamine, Ginkgo Biloba, N-acetyl L-carnitine (NAC or NALC), and Huperzine A in formula boost brain function, mental performance and give mental clarity
Quantity In Each Pack: 30 pills
Right Serving: Serve one pill
Any Guarantee: 60 days money-back guarantee
ReMind Solution Price: $69

ReMind Solution (a.k.a. ReMind) takes the time to seek out ingredients that already have clinical support behind them. The evidence takes little time to find, but the formula explicitly includes elements that eliminate brain fog, reduce anxiety, stress and focus issues. Also, it can boost memory, support healthy brain function, and improve cognitive function. However, the problem with this formula has nothing to do with the quality. Instead, the issue is the high price versus value.

Brain Pill

Supplement Description
What’s In There? The Brain Pill Formula contains Citicoline, tyrosine, L-theanine, and vitamin B12 (plus other ingredients) to enhance cognitive abilities and mental performance
Quantity In Each Pack: 60 pills
Right Serving: Two pills daily to boost memory and mental performance
Any Guarantee: 67 days money-back guarantee
BrainPill Price: $69.95

BrainPill’s creators entice consumers claiming that this remedy offers an “unfair advantage” over the other nootropic supplements in the market today. It reduces the amount of brain fog with the user, though it also supports brain power, mental performance, mental clarity, and overall cognitive performance. Each of the servings of Brain Pill contains 13 nootropics for these effects, thanks to work done by Dr. Dave David.

The Brain Pill formula comes at a higher cost, but there are no dosages listed, and the lack of transparency makes choosing this formula tricky. Still, they claim to offer Brain Pill with “hefty” and “proper” doses for users.

ProMind Complex

Supplement Description
What’s In There? L-glutamine, phosphatidylserine, Bacopa Monnieri extract, vinpocetine, and Huperzine A
Quantity In Each Pack: 30 pills
Right Serving: Serve one pill every day
Any Guarantee: Money back guarantee of 60 days
ProMind Complex Price: $69

ProMind Complex is the result of Carl Henderson’s work, as well as his team. There isn’t much said about Carl but the idea that he’s been involved in developing this nootropic remedy for decades. The active ingredients and dosages aren’t entirely on par with the other remedies on this list.

Memory Hack

Supplement Description
What’s In There? Green tea, Bacopa Monnieri, Artichokes Leaf, and Omega Fatty Acid
Quantity In Each Pack: 60 capsules
Right Serving: Serve two capsules
Any Guarantee: Users have up to 60 days to get a refund if the formula doesn’t satisfy their needs
Memory Hack Price: $69

Memory Hack, which is by Nutrition Hacks, has several essential ingredients, but it falls short in the potent doses that other formulas on this list have (which is why it doesn’t have a high spot). The advertised benefits grab users’ attention, stating that anyone who uses the product will completely restore the user’s memory in a matter of 6 months.


Supplement Description
What’s In There? Phosphatidylserine, N-Acetyl-L-Carnitine, Bacopa Monnieri Extract, and more
Quantity In Each Pack: Contains 30 capsules
Right Serving: Take one pill
Any Guarantee: Money back guarantee of two months
MemoSurge Price: $69

MemoSurge helps users with three different steps, improving the brain’s neurotransmitters to improve the damaged cells. When users take the supplement initially, the neurotransmitters already get the fired-up support that they need. Then, the brain cells damage starts repairing while reducing brain shrinkage. Also, it promotes the production of new brain cells. Finally, anxiety and insomnia subside, increasing energy levels in the process.

Memo Defend

Supplement Description
What’s In There? The whole formula comprises a proprietary blend, which provides hawthorn leaf, garlic bulb, and olive leaf
Quantity In Each Pack: 60 pills
Right Serving: Serve two pills daily
Any Guarantee: Money back guarantee of 60 days
Memo Defend Price: $69

Memo Defend, created by Thomas Taylor, is all about natural ingredients, though it is relatively low on the list. The cognitive enhancer can enhance cognitive performance, nervous system and improve brain health. There’s very little information about any type of lab testing, the doses included, or even the ingredients themselves. The clinical studies available on its ingredients have a limited connection to nootropic formulas. Still, users get a massive dose of vitamin B12. Vitamin B12 can boost your mood and aid in brain cell development.

How the Best Nootropics Were Ranked

Since the promises are so similar between these formulas, this guide had to find the best way to differentiate between good and ineffective. With considerations like lab reports and ingredient profiles, the decision was quite clear. Here’s a little explanation of the information considered while selecting the best nootropic supplements.

Science-Backed Ingredients

The ingredients in each formula had to have some kind of proof to back them up. Plant extracts, vitamins, minerals, and herbs all have studies that show exactly how they benefit consumers naturally, though they need consistent use with effective doses. The best nootropic supplements with better spots on this list were the ones with ingredients already backed by science.

Effective Dosages

As stated above, the dosage used for these ingredients is just as crucial as getting the proper dosage. Each nootropic supplement formula needs a high enough concentration to have a positive effect on the body. Without this concentration, the formula doesn’t work.

Transparent Advertised Benefits

Since nootropic formulas often have a powerful effect on the brain, companies exaggerate how much support users can get from them. Some brands state that the brain magically becomes younger, while others create a feeling of cognitive energy for their mind. The best nootropic supplements with priority were the ones who were honest about the benefits that they advertised.

Manufacturer Lab Testing and Clinical Trials

Creating a nootropic supplement is making sure that it will work, which many companies verify with lab testing. Companies often use a third-party lab to create more transparency with their brand, but many companies avoid the testing altogether. The best nootropic supplements focus on clinical trials on their products, studying the ingredients individually and the formula altogether.

Customer Reviews

Everyone has different experiences while using nootropic supplements, but they aren’t perfect. Different experiences ensue, which is why money-back guarantees are so necessary. However, that’s why the guide also considered the reviews of current customers to see if the formulas worked.

Price & Value

People want to know that the money they spend on nootropic supplements is worth it. For some people, that price is relatively high at $200 per month. Still, others would prefer to only use about $20 out of their monthly budget to invest in nootropic remedies.

Nootropic Supplements and Their Ingredients: How Well Do They Work?

Considering some of the brands of today, bold claims and major promises are relatively common among nootropic supplements. If these brain supplements work, how do nootropics and smart drugs benefit users? Is there any science behind the ingredients that they use?

A few short years ago, the world of nootropic remedies was barely a field of interest among researchers. Now, multiple researchers assist in peer-reviewing these ingredients, supporting the remedies with decades of tests on both animals and humans.

One of the most popular ingredients in these formulas is Bacopa Monnieri, which is an herbal extract. It already has hundreds of years of use in history, though it has primarily been used in traditional Chinese medicine. There’s a study from 2001 that shows the potential effects of this ingredient include improved cognition, following participants for 12 weeks. It also helped users to promote better learning and memory.

Luckily, plenty of studies on Bacopa Monnieri shows precisely why it is an essential remedy for nootropic supplements. Another study – in 2008 – demonstrated that this substance was beneficial to older individuals, which is due to the bacosides that naturally occur in it. Many supplement companies that use the ingredient will include the total amount of bacosides on the label, averaging about 300-600 mg daily.

Ginkgo Biloba is another popular ingredient, and it also offers the nostalgia of centuries of use. By combining it with a nootropic ingredient called vinpocetine, researchers discovered that just 14 days of use improved memory significantly in a 2001 study.

Ashwagandha is an adaptogen, but its use in nootropic supplements is primarily due to the soothing effect on the mind. Typically used in traditional Indian medicine, Ashwagandha it’s mainly known for the relaxation and stress reduction it provides. It also supports cardiovascular health, and many supplements include it in their nootropic or smart drugs. It reduces neurotoxins in the brain, protecting it from damage to memory and decreased cognition.

Today’s top products on the market focus on improving cognition, supporting a better mood, and improving memory. However, there are many effects that nootropic supplements can have. By checking out one of the products above, it is easy to determine which one will work for the customer. If not, the majority of the remedies have a money-back guarantee.

Frequently Asked Questions About Nootropics

Q: What is a nootropic?

A: A nootropic is often a supplement companies offer in food, beverage, or other products to increase cognition and support brain function.

Q: What do nootropics and smart drugs do?

A: Generally, these formulas improve the user’s brain health in different ways. Some formulas are created for memory function, while others stimulate mental energy with caffeine and other stamina-inducing ingredients. Users can browse through many options online to find the best nootropic remedy for their particular needs.

Q: How do users take nootropics?

A: It depends on the formula. These brain supplements have many forms, including edible treats, capsules, powders, and other options. Users only need to take about one or two capsules for the majority of these nootropic supplements to get the desired benefits. Always read through the instructions to ensure the best chance of results.

Q: What’s the top nootropic supplement on the market now?

A: Any of the formulas on this list would be excellent options for users.

Q: What are the benefits of using a nootropic supplement?

A: Taking a nootropic supplement or smart drugs is incredibly helpful to the user’s memory, cognition, and brainpower. Some of the formulas focus on specific concerns, including memory problems or mood. The nootropic supplements on the market today will say the type of benefit that users can expect right on the label.

Q: Who benefits from a nootropic supplement?

A: Anyone can benefit from smart drugs. Individuals who compete competitively, college students who need more focus, parents who feel exhausted, and anyone else will likely find why this type of boost helps them.

Q: Are nootropics legal?

A: Yes. Currently, every single state allows the use of nootropics and smart drugs. The only thing that these nootropics supplements have to do to be legal is to follow the guidelines of the FDA.

Q: Are nootropics natural?

A: Many times, they are. Companies will include natural ingredients, vitamins, minerals, and extracts that expand the mind. Still, synthetic ingredients might be in certain brands that want to curate their effect. It is always best to check the label to find out for sure.

Q: Do users need prescriptions to get access to nootropics?

A: No. Nootropic supplements are freely available online and in stores. Individuals with memory issues and other cognitive concerns may want to speak with the doctor about treating them.

Q: What is the best time to take a nootropic supplement?

A: To start their day off right, most consumers prefer to take a nootropic supplement by early afternoon or the morning. Stimulants are not for late-night use, which is why users should check to see if they are in the particular product they choose.

The Top 33 Nootropic Supplements in 2021 Final Thoughts

Using nootropic supplements is incredibly common nowadays. Formulas seem to be available everywhere customers turn, making it harder to choose which one is right. They come in many formats, made to fit a variety of budgets. The right nootropic will provide support for memory, cognition, and more. They are for anyone that needs a boost in their mental energy, and this list offers a selection of options. With over 30 different remedies available, customers start wherever they feel comfortable on their journey to improved brain health.

RELATED:5 Best Adderall Alternatives: Top Natural OTC Brain Supplements

Affiliate Disclosure:

The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

The news and editorial staff of Sound Publishing, Inc. had no role in the preparation of this post. The views and opinions expressed in this sponsored post are those of the advertiser and do not reflect those of Sound Publishing, Inc.

Sound Publishing, Inc. does not accept liability for any loss or damages caused by the use of any products, nor do we endorse any products posted in our Marketplace.